Absolute stereostructures of olibanumols A, B, C, H, I, and J from olibanum, gum-resin of Boswellia carterii, and inhibitors of nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages.

نویسندگان

  • Masayuki Yoshikawa
  • Toshio Morikawa
  • Hideo Oominami
  • Hisashi Matsuda
چکیده

Three new monoterpenes, olibanumols A (1), B (2), and C (3), and three new triterpenes, olibanumols H (4), I (5), and J (6), were isolated from olibanum, the exuded gum-resin from Boswellia carterii BIRDW. Their structures including the absolute configuration were determined by chemical and physicochemical evidence. Among the constituents, olibanumols A (1), H (4), and I (5), and isofouquierol (12) exhibited nitric oxide production inhibitory activity in lipopolysaccharide-activated mouse peritoneal macrophages.

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عنوان ژورنال:
  • Chemical & pharmaceutical bulletin

دوره 57 9  شماره 

صفحات  -

تاریخ انتشار 2009